The Howard Hughes Medical Institute is a nonprofit medical research organization that engages in the direct conduct of research in the basic life sciences. The Institute also has a vibrant grants program focused on strengthening education in biology and related sciences.

The Institute’s charter states, “The primary purpose and objective of the Howard Hughes Medical Institute shall be the promotion of human knowledge within the field of the basic sciences (principally the field of medical research and medical education) and the effective application thereof for the benefit of mankind.”

HHMI’s flagship research programs currently include 325 Investigators and 45 Early Career Scientists, in HHMI-supported laboratories at 75 U.S. universities, research institutes, medical schools, and affiliated hospitals. These scientists employ and train nearly 700 postdoctoral associates and provide educational opportunities for more than 1,000 graduate students each year.

For its Investigators and Early Career Scientists, HHMI has long viewed the sharing of research materials and tools as a fundamental responsibility of scientific authorship. That principle also extends to ensuring that original, peer-reviewed research publications and supplemental materials are freely accessible within six months of publication. The Institute’s policy on public access to publications took effect for manuscripts submitted for publication on January 1, 2008.